Interactions and Membrane Structure
نویسندگان
چکیده
olipin and is responsible for increased catalysis, whereas direct interaction between CT V< 5 and acidic PLA 2 inhibits enzyme activity. It is concluded tha t variabilít} in substrate composition and the chemical nature of both PLA 2 and cationic peptide determine whether enzyme activity is affected by substrate packing or by direct enzyme-peptide interaction. Models of interactions of PLA 2 with CT V c5 and phospholipid membranes are presented. K e y words: Snake venom PLA 2 — Cytotoxin V c5 — Phospholipid membranes — Fluorescence displacement — E P R — 3 1 P-NMR Correspondence to: Professor Eppie D. Rael, Department of Biological Sciences, University of Texas at El Paso, El Paso, TX 79968-0519, USA
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